Aug 17

Clinical Study – Subclinical Bacteriuria in Dogs with CKD

Clinical Study – Subclinical Bacteriuria in Dogs with CKD

Friendship Internal Medicine is now recruiting patients for a fully funded clinical study of “Subclinical Bacteriuria in Dogs with CKD.”

How do you approach a positive urine culture in a dog without any clinical signs?

Veterinary infectious disease experts have recommended that these dogs do not require therapy. However, diseases like chronic kidney disease (CKD) may increase the risk of ascending urinary tract infection. Currently, data isn’t available to help guide treatment recommendations.

Our goal is to change that.

We are looking to enroll dogs with CKD and a positive urine culture, who lack clinical signs of lower or upper urinary tract infection.

This study is fully funded. All dogs will receive the following at no cost to the owners:

  • Exam by internal medicine specialist
  • Recheck urine culture to confirm bacteriuria
  • Complete blood count
  • Biochemical panel
  • Urinalysis
  • Urine protein:creatinine ratio
  • Urinary tract ultrasound
  • Analysis of serum and urinary renal injury biomarkers

Dogs will not receive antibiotic therapy throughout the duration of the study unless clinical signs of infection develop. Dogs with clinical signs of urinary tract infection at the time of enrollment will be treated with appropriate antimicrobials and not be eligible for enrollment.

All dogs will receive complimentary recheck examinations and free labwork at 1, 3, and 6 months after enrollment.

Please contact Friendship Internal Medicine to discuss enrolling your patient in this study.


Friendship Internal Medicine, led by Dr. Gideon Daniel, Dr. JD Foster, Dr. Denise Kelley, and Dr. Erick Spencer, are board-certified veterinary internists.  Specially trained to treat a wide variety of conditions in respiratory disease, endocrinology, hematology, gastroeneterology, liver disease, nutrition, nephrology, urology, immune-mediated diseases, infectious diseases, and more.



 *Featured image courtesy of Blue Pearl Vet.

Friendship provides state of the art, comprehensive services for our clients and patients. But, more than that, we provide a caring team who understand the unique human-animal bond. View Our Services